{"product_id":"kolorex-advanced-candida-care-30-capsules","title":"Kolorex Advanced Candida Care | 30 Capsules","description":"\u003ch2\u003eKolorex® Advanced Candida Care\u003c\/h2\u003e\r \u003ch3\u003eWhat is Kolorex?\u003c\/h3\u003e\r \u003cp\u003eKolorex Advanced Candia Care capsules provide natural herbal support for maintaining healthy levels of the yeast Candida albicans in the body, to help prevent infections like candidiasis and to maintain the important balance in gut microflora.\u003c\/p\u003e\r \u003ch3\u003eWhy use Kolorex?\u003c\/h3\u003e\r \u003cp\u003eKolorex Advanced Candia Care capsules contain a concentrated natural herbal extract made from Horopito, an ancient New Zealand plant used in traditional medicine and with known antifungal properties.  Kolorex Advanced Candia Care capsules provide support for maintaining healthy levels of the yeast fungus Candida albicans in the body, to maintain the important balance in gut microflora and to help prevent overgrowth Candida, which can result in infections like candidiasis or thrush.\u003c\/p\u003e\r \u003ch3\u003eWhat are the Key Benefits of Kolorex?\u003c\/h3\u003e\r \u003cul\u003e\r     \u003cli\u003eTraditional medicinal plant organically grown \u003c\/li\u003e\r     \u003cli\u003eProvides natural support for maintaining healthy gut flora and normal intestinal Candida levels\u003c\/li\u003e\r     \u003cli\u003eHelps prevent the yeast infection candidiasis (thrush)\u003c\/li\u003e\r     \u003cli\u003eEasy to swallow once a day soft gel capsules containing high potency liquid extract\u003c\/li\u003e\r     \u003cli\u003eDoes not contain added colours, flavours, preservatives\u003c\/li\u003e\r     \u003cli\u003eFree of gluten, wheat, dairy\/casein, soy, corn, yeast, nuts\/peanuts\u003c\/li\u003e\r \u003c\/ul\u003e\r \u003ch3\u003eWhat is Candida?\u003c\/h3\u003e\r \u003cp\u003eCandida is a yeast fungus that normally lives in the body without causing any problems.  It is found on the skin and in the moist mucous membranes such as in the intestines, mouth, throat and vagina, as part of our normal body flora.  Under certain conditions the yeast becomes overgrown and then becomes a fungal infection known as candidiasis, such as if the skin becomes broken, when taking antibiotics or if you have diabetes or a weakened immune system.\u003c\/p\u003e\r \u003ch3\u003eWhat is Candidiasis (thrush)?\u003c\/h3\u003e\r Candidiasis is an infection with the yeast fungus Candida albicans, also known as thrush.  The most common Candida infections are:\r \u003cul\u003e\r     \u003cli\u003eOropharyngeal Candidiasis or oral thrush (mouth and throat) with symptoms including white patches on the tongue and soreness when swallowing\u003c\/li\u003e\r     \u003cli\u003eVaginal Candidiasis or thrush of the vagina with symptoms including itching, burning sensation, and a white cheese-like discharge\u003c\/li\u003e\r     \u003cli\u003eCutaneous Candidiasis or candida infection of the skin and nails with symptoms including crumbling nails, red scaly itchy patches of skin, such as between the toes or in folds of skin. \u003c\/li\u003e\r \u003c\/ul\u003e\r \u003ch3\u003eWhat is the Intestinal Microflora?\u003c\/h3\u003e\r \u003cp\u003eThe normal intestinal or gut microflora is made up of many microorganisms including bacteria that help with the digestion of our food, and the yeast fungus Candida albicans, one of the microorganisms that live in balance with the gut community, doing no harm but providing no benefit, known as commensalism.  Other microorganisms play a role in helping maintain the integrity of the gut wall and protecting against harmful pathogens.  It is well recognised that a healthy gut flora is important for overall health and wellness and depends on a balance between microorganisms that are beneficial and those that are harmful.  When the balance is tipped then microorganisms that are beneficial become displaced by the overgrowth of harmful microorganisms, which results in an infection or in other symptoms such as bloating, digestive disturbance and may cause more serious problems like irritable bowel disease.  Factors that can tip the balance include poor diet, alcohol, stress, antibiotics and some medications\u003csup\u003e1.  \u003c\/sup\u003e\u003c\/p\u003e\r \u003ch3\u003eWhat are the Ingredients of Kolorex?\u003c\/h3\u003e\r \u003ch4\u003eHoropito \u003cem style=\"color: inherit; font-family: inherit; font-size: 14px;\"\u003e(Pseudowintera colorata):\u003c\/em\u003e\n\u003c\/h4\u003e\r \u003cp\u003eHoropito is an ancient evergreen shrub belonging to the Winteraceae family and native to New Zealand.  It is also known as pepperwood due to the spicy taste of its leaves.  For hundreds of years, Horopito has been used a traditional medicinal herb the indigenous Maori for skin diseases, including fungal infection and digestive problems, and the leaves were chewed for toothache.  Early European settles also used Horopito for medicinal purposes such as for stomach ache2.  This unique New Zealand herb is now grown organically by Forest Herbs Research, a Nelson-based private company dedicated to the production of Horopito as a medicinal herb for treatment and prevention of Candida infections.  Horopito plants vary in their antifungal activity and the extract used for Kolorex is made from only the most active strain, which are leaves containing red margins\u003csup\u003e2, 3.  \u003c\/sup\u003e\u003c\/p\u003e\r \u003ch4\u003eAntifungal properties \u003c\/h4\u003e\r \u003cp\u003eThe leaves of the Horopito plant contain many bioactive compounds including terpenes, particularly polygodial, a sesquiterpene dialdehyde.  The highest concentrations of polygodial were found in the red margined leaves\u003csup\u003e2,\u003c\/sup\u003e \u003csup\u003e3.\u003c\/sup\u003e  The extract used for Kolorex is prepared as an oleoresin, which is a combination of oil and resin that contains a highly concentrated amounts of polygloidal and exists in liquid form\u003csup\u003e2.\u003c\/sup\u003e  Extracts of Horopito leaves containing polygloidal were investigated for their antifungal activity and found to be effective against the yeast fungus Candida albicans that causes candidiasis or thrush\u003csup\u003e4,\u003c\/sup\u003ealso against other fungal pathogens\u003csup\u003e4, 5.\u003c\/sup\u003e  The antifungal activity of polygloidal was investigate and found to be primarily due to disruption of the fungal cell membrane causing it to leak its intracellular contents resulting in fungal cell death\u003csup\u003e6, 7.  \u003c\/sup\u003e\u003c\/p\u003e\r \u003ch4\u003eClinical studies\u003c\/h4\u003e\r \u003cp\u003eStudies in women with recurrent vaginal candidiasis demonstrated that Kolorex is equally effective as the antifungal medication itraconazole, as a treatment for reducing symptoms of candidiasis and preventing further infections by eliminating the yeast.  Kolorex was also found to be more effective than itraconazole as maintenance treatment in preventing relapses\u003csup\u003e8, 9.  \u003c\/sup\u003e\u003c\/p\u003e\r \u003ch4\u003eOther Ingredients:\u003c\/h4\u003e\r \u003cp\u003eKolorex Advanced Candia Care soft gel capsules also contain olive oil, gelatin (bovine source, halal certified), glycerine and purified water.\r \u003c\/p\u003e\r \u003ch3\u003eWhat are the Contraindications\/Interactions of Kolorex?\u003c\/h3\u003e\r \u003cp\u003eDo not use if you are pregnant or breastfeeding, and do not give to children, as there is no clinical evidence for safety during pregnancy or in children.\u003cbr\u003e\r Stop using if you develop any irritation or allergy while taking Kolorex.  Always read the label and use as directed and seek advice from your healthcare professional.\u003c\/p\u003e\r \u003ch3\u003eWhat are the Directions for using Kolorex?\u003c\/h3\u003e\r \u003ch4\u003eDosage:\u003c\/h4\u003e\r \u003cp\u003eTake your Kolorex Advanced Candia Care soft gel capsules once daily, swallowed whole with a glass of water.\u003c\/p\u003e\r \u003ch3\u003eReferences\u003c\/h3\u003e\r \u003ch5\u003eThe following references provide scientific support for the use of this product:\u003c\/h5\u003e\r \u003col\u003e\r     \u003cli\u003eJandhyala SM, Talukdar R, Subramanyam C, Harish Vuyyuru H, Mitnala Sasikala M, Reddy DN Role of the normal gut microbiota. World J Gastroenterol 2015 Aug 7; 21(29): 8787–8803.\u003c\/li\u003e\r     \u003cli\u003eForest Herbs Research, Scientific Summary Version 13 (Aug 2016) http:\/\/www.kolorex.com\/wp-content\/uploads\/2016\/08\/FHR-Scientific-Summary-V13-August-2016.pdf \u003c\/li\u003e\r     \u003cli\u003eCooney LJ, van Klink JW, Hughes NM, Perry NB, Schaefer HM, Menzies IJ, Gould KS. Red leaf margins indicate increased polygodial content and function as visual signals to reduce herbivory in Pseudowintera colorata. New Phytol. 2012 Apr;194(2):488-97. \u003c\/li\u003e\r     \u003cli\u003eMcCallion R.F., Cole A.L.J., Walker J.R.L., Blunt J.W., Munro M.H.G. Antibiotic substances from New Zealand plants. II. Polygodial, an anti-Candida agent from Pseudowintera colorata. Planta Med. 1982;44:134–138.\u003c\/li\u003e\r     \u003cli\u003eLee, S.H.; Lee, J.R.; Lunde, C.S.; Kubo, I. In vitro antifungal susceptibilities of Candida albicans and other fungal pathogens to polygodial, a sesquiterpene dialdehyde. Planta Med. 1999, 65, 204–208.\u003c\/li\u003e\r     \u003cli\u003eTaniguchi, M., Yano, Y., Tada, E., Ikenishi, K., Oi, S., Haraguchi, H., Hashimoto, K. \u0026amp; Kubo, I. (1988). Mode of Action of Polygodial, an Antifungal Sesquiterpene Dialdehyde. Agricultural and Biological Chemistry, 52(61), 1409–1414. \u003c\/li\u003e\r     \u003cli\u003eKubo I., Fujita K., Lee S.H. Antifungal mechanism of polygodial. J. Agric. Food Chem. 2001;49:1607–1611.\u003c\/li\u003e\r     \u003cli\u003eKumari A, Bishier MP, Naito Y, Sharma A, Solimene U, Jain S, Yadava H, Minelli E, Tomella C, Marotta F. Protective effect of an oral natural phytonutrient in recurrent vulvovaginal candidiasis: a 12-month study. J Biol Regul Homeost Agents 2011 Oct-Dec;25(4):543-51.\u003c\/li\u003e\r     \u003cli\u003eChopra V., Marotta F., Kumari A., Bishier M.P., He F., Zerbinati N., Agarwal C., Naito Y., Tomella C., Sharma A., Solimene U. (2013) Prophylactic strategies in recurrent vulvovaginal candidiasis: a 2-year study testing a phytonutrient vs itraconazole. Journal of Biological Regulators and Homeostatic Agents, 27(3):875-82. \u003c\/li\u003e\r \u003c\/ol\u003e","brand":"Kolorex","offers":[{"title":"30caps","offer_id":31177699819565,"sku":"00351-30caps","price":25.65,"currency_code":"NZD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9954\/6157\/products\/1120261.jpg?v=1573461184","url":"https:\/\/nz-nutristrong.myshopify.com\/products\/kolorex-advanced-candida-care-30-capsules","provider":"NZ NutriStrong","version":"1.0","type":"link"}