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Go Healthy Go Hair Skin Nails Beauty Support | 50 VegeCapsules

Go Healthy Go Hair Skin Nails Beauty Support | 50 VegeCapsules

$26.04
$26.04
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Go Health Go Hair Skin Nails Beauty Support

What is Go Hair Skin Nails Beauty Support?

Go Hair Skin Nails is a dietary supplement containing a blend of specific ingredients designed to support healthy hair, skin and nails. The high strength formula in Go Hair Skin Nails provides antioxidant protection against skin damage and improves the appearance of skin by reducing visible signs of damage and aging; it also improves the strength and condition of hair and nails.

Why use Go Hair Skin Nails Beauty Support?

Go Hair Skin Nails Beauty Support contains natural marine collagen which helps to improve the skin’s appearance, including fine lines. With increasing age, the body’s natural ability to produce new collagen declines and existing collagen begins a natural regression of breaking down. This loss is due to aging of our skin, joints and bones which ultimately can lead to other health problems such as digestive issues, a weakened immune system and increased risk of chronic illness. Natural marine collagen has superior absorption and bioavailability and has the smallest particle size and lowest molecular weight among all collagen types, which allows it to pass through the intestinal wall into the bloodstream more easily to promote better healing, repair and nourishment benefits. This is one of the most effective collagens because it is so much more efficiently absorbed than other types. One of the most fundamental minerals our bodies require is Silica. It’s an essential beauty mineral that helps to heal brittle bones, teeth, hair and nails. It also has anti-aging and anti-wrinkle properties to help form collagen and repair damaged, stretched and sagging skin. Silica is actually one of the biggest components of collagen. When collagen is depleted or damaged in the skin, which incidentally is occurring all of the time as we age and due to free radical damage, the action of Silica is to take care of this by rebuilding and regenerating the connective tissue. Silica has many benefits, for example it helps to combat mild to moderate acne as it helps to enhance collagen production which ensures healthy outer cell layers of the skin which are less likely to become inflamed from the hormonal waste that is associated with acne. Silica also works as a great supplementation for the removal of toxins which arise as a result of digestion. These toxins leak into the bloodstream, causing inflammation which leads to acne and dull, lifeless skin. Another important role of Silica is that it takes all of the nutrients to the nails helping to strengthen them but also feeding the nail bed with vital nutrients needed for growing healthy and strong nails.

What are the Key Benefits of Go Hair Skin Nails Beauty Support?

  • Contains high potency Silica, Horsetail and Biotin for increased nail thickness and shiny hair
  • Contains antioxidants to protect the skin from damage
  • Contains herbal extract, minerals and vitamins that support healthy nails and hair
  • Helps to prevent nail splitting as well as chipping, breakage, spotting and ridges
  • Improves skin’s texture minimising fine lines
  • Promotes skin suppleness
  • Promotes healing, repair and nourishment to brittle hair, skin and nails
  • Reduces acne and breakouts
  • Prevents hair thinning and hair loss
  • Does not contain additives or preservatives
  • Free from animal products like gelatine

What is photoaging?

Continued exposure to ultraviolet (UV) radiation from the sun causes photoaging of the skin, which is premature aging, not related to actual age in chronological terms. Photoaging affects all the layers of the skin and causes major structural changes. The epidermis contains melanocytes that produce the pigment melanin. UV causes increased melanin, which changes the colour of the skin (suntan), but also produces sun spots or age spots that are irregular in shape and accumulate in patches. UV exposure causes oxidative stress in the skin producing free radicles that cause damage to skin cells and to their DNA. UV exposure also triggers inflammatory responses intended to help repair the damage caused. However, the inflammatory cytokines produced create further problems by inducing the production of enzymes known as matrix metalloproteinases (MMPs) by keratinocytes (skin cells) in the epidermis (outer skin layer), also dermal fibroblast. These MMPs degrade collagen and elastin (important structural proteins), which disrupts the structure of the skin, causing deep wrinkles and loss of skin elasticity; also, water loss, as the ability to retain moisture is compromised by the damaged skin. Extreme exposure of the skin to UV can damage the DNA and lead to skin cancer1, 2.

What is an antioxidant?

Antioxidants are stable compounds that protect the body against free radicals. Some antioxidants like glutathione occur naturally in the body; also plants are a rich source of natural antioxidants, mainly polyphenols such as flavonoids, procyanidins (proanthocanidins), lignans and stilbenes; triterpenoid; vitamins such as vitamins C and E, and carotenoids like xanthophylls and carotenes.

What is the hair growth cycle?

Healthy hair is the sign of a healthy body. Growth of healthy hair is dependent on micronutrients including vitamins and minerals that nourish hair, promote the circulation supporting the hair follicle, and protect against oxidative damage. The condition of hair may be influenced by a poor diet or nutrient deficiency, an illness, or a skin condition that affects the scalp. The hair follicle is the unit that produces a single hair and it has its own growth cycle that can last up to 9 years in total. The hair root sits at the base of the hair follicle deep in the dermis of the skin. The follicle passes through the dermis into the epidermis, where the hair emerges. The follicle contains two areas of actively diving stem cells; in the bulb at the base and in the bulge in the middle, that are both responsible for new hair growth at different stages of the hair growth cycle. The follicle is nourished by the sebaceous glands and small blood vessels, and hair growth is regulated by hormones and growth factors. Hair growth has four distinct phases, which vary in length in different parts of the body. Anagen is the phase of active growth and can last for 2-6 years for scalp hair. The catagen phase is when hair growth slows down and is known as the regression phase lasting a few weeks. Telophase is the resting phase and after a few months, the fully grown hair stops growing and becomes a club hair, which is effectively a dead hair and contains keratin, which is an important structural protein for healthy strong hair. This is the hair that emerges onto the scalp. At this stage the hair has detached from the base of the follicle and the new hair forming beneath it pushes the old hair out and it is eventually shed. Hair growth is a continuous cycle of renewal and any disruption in the hair cycle can cause hair loss3, 4.

How are nails formed?

As with hair, nails are important indicators of general health and nutritional status. Nails are a growing structure and made up mainly of keratin, an important fibrous structural protein found in hair and nails and the outer layers of skin. The nail root or germinal matrx is where the cells that form the nail originate and its edge can be seen under the skin as a white crescent or lunula beneath the nail. The eponychium is the area of living skin beyond the proximal nail fold (paronychium) and leads to the cuticle. This part of the nail structure is essential for sealing and protecting the emerging nail from bacteria and other microorganisms. The nail plate (hyponychium) is made up of many layers of thickened dead keratinised cells that protect the underlying soft living tissue of the nail bed and these two layers are firmly attached until they reach the tip of the finger, where they separate allowing the nail to continue to grow. The cells of the matrix continually produce new keratin which accumulates at the nail plate, slowly pushing the nail forward so that it grows over the nail bed at a rate of 2-3mm per month. Complete replacement of a nail takes 6-9 months. Good nutrition is important for maintaining healthy nails and a range of vitamins and minerals are essential for supporting nail growth and development. Any deformities in any part of the nail can cause structural problems such as trachyonychia, with is a disease of the nail matrix and is also associated with inflammation, aloplecia (hair loss) and skin conditions like psoriasis and lichen planus (a condition that causes swelling and irritation of the hair, skin, nails and mucous membranes5, 6.

What are the Ingredients of Go Hair Skin Nails Beauty Support?

Each VegeCapsule of Go Hair Skin Nails contains: 
  • Natural Marine Collagen 100mg
  • Horsetail (Equisetum arvense) 6000mg (extract equivalent)
  • Vitamin B6 (pyridoxine) 8mg
  • Vitamin B7 (Biotin) 1.3mg
  • Vitamin C (Ascorbic acid) 60mg
  • Vitamin D3 500IU
  • Vitamin E 40IU
  • Selenium 50mcg
  • Silica (Colloidal anhydrous) 60mg
  • Zinc citrate 50mg

Key Ingredients:

Multicomponent supplements:

Beneficial effects on skin structure and physiology have been demonstrated using supplements containing selected clinically tested components, particularly when used in combination. These include collagen peptides, vitamins, minerals and antioxidants. Although collagen peptides alone can protect skin against the effects of damage and aging, these effects are enhanced by using multicomponent supplements7.

Natural Marine Collagen:

Collagen is one of the most abundant proteins in the body and is group of important structural proteins found in the connective tissue throughout the body that provides structural support for all tissues, as well as regulating the way different cells and tissues function. Collagen is a fibrous protein with great tensile strength and is made up of many tiny fibrils formed in a triple helix structure. There are five types of collagen distributed throughout various tissues. Type l is the most common collagen type and is found in the dermis of skin, providing support and elasticity, due to its helical structure; also in bone, tendons, ligaments, teeth and nails. The structure and amino acid composition of collagen is preserved across species which means it is biocompatible between species. This includes marine collagen, which offers an alternative collagen source for use in pharmaceuticals, cosmetics or biomedical applications and has the added benefit of making use of waste products of processing, and with no known cross species infective agents. Marine collagen is extracted from many fish species (skin and scales), and marine invertebrates like sponges, sea urchins and jellyfish, and comprises mainly type I collagen8, 9, 10, 11. Hydrolysis is an enzymatic process for reducing a protein to its constituent peptides of small chains of amino acids that are the building blocks of proteins. Hydrolysed fish collagen is a pure form of small, low molecular weight peptides, which are easily digested and more easily absorbed and distributed, with improved bioavailability over mammalian collagen and with comparable bioactive properties10, 12, 13. In vitro studies investigating the role of collagen peptides from fish skin on normal human cultured dermal fibroblast demonstrated increased elastin production, decreased matrix metalloproteinases (MMP) production and reduced elastin degradation. These effects were enhanced by the presence of antioxidants like resveratrol, indicating that supplements containing collagen peptides and antioxidants contribute to a stable extracellular matrix (ECM) produced by dermal fibroblasts14. Animal models have been used to demonstrate that marine collagen peptides promote wound healing and collagen synthesis, also enhanced skin immunity, reduced water loss, restored skin collagen and elastin levels, and reduced collagen breakdown by matrix MMPs. These findings indicate that marine collagen peptides are effective in improving skin elasticity and hydration and protecting against photoaging15, 16, 17. The outcomes of a clinical study with healthy volunteers, indicate that skin elasticity and structure improved following supplementation with a combination of collagen peptides and antioxidant vitamins C and E18. The outcomes of clinical studies with healthy volunteers have shown that supplementation with hydrolysed marine collagen peptides, alone or in combination with plant derived antioxidants, improved skin properties by improving the density and integrity of the collagen network, increasing collagen and elastin content, resulting in improved elasticity, skin thickness and moisture content. These studies suggest that supplementation with collagen peptides is beneficial in improving the visible signs of aging15, 19, 20, 21, 22.

Horsetail (Equisetum arvense):

Horsetail is a prehistoric plant dating back to the Palaeozoic era 400 million years ago and found throughout Europe, Asia and North America and into the Arctic Circle. Since ancient times Horsetail been used in traditional medicine to stop bleeding, heal wounds and treat kidney and bladder problems. Extract of horsetail is rich in bioactive chemicals including alkaloids, triterpenoids, flavonoids, phenolics and tanins, which contribute to its many biological properties including antioxidant, anti-inflammatory antibacterial, diuretic and wound healing23, 24, 25. Horsetail extract is rich is silica, which is known to support calcium absorption and also promote collagen synthesis, which is important in maintaining healthy skin, bones and connective tissue. Silica has been used to strengthen teeth, hair and nails 23, 26. A topical application containing horsetail extract improved nail fragility and reduced nail splitting and malformation27.

Vitamin B6 (pyridoxine):

Like all members of the vitamin B group pyridoxine is a cofactor for many enzymes that perform many metabolic functions throughout the body and is important for energy production, immune function and formation of red blood cells. Pyridoxine Pyridoxal 5’ phosphate (PLP) and pyridoxamine 5’ phosphate (PMP) are the active coenzyme forms of vitamin B6. Pyridoxine is an essential cofactor in the folate/methionine cycle that result in the generation of amino acids for protein synthesis and is needed for cell biosynthesis and production of important molecules such as the natural antioxidant glutathione. Pyridoxine is also needed for generation of nucleic acids for DNA and RNA synthesis. Rapidly dividing cells like skin cells and hair follicles require sufficient amount of B6. Keratin is synthesised from the amino acids cysteine and methionine and this process is B6 dependant28, 29.

Biotin (vitamin B7):

The B vitamins are a family of water soluble vitamins that play important roles in many essential physiological processes. Biotin or vitamin B7 is an essential cofactor for five different carboxylase enzyme that are involved in metabolic pathways for fatty acid synthesis, glucose metabolism (citric acid cycle) and amino acid metabolism28, 30. Biotin is an essential cofactor for synthesis of keratin, an integral structural protein of hair, skin and nails. Signs of biotin deficiency include dermatitis, which is thought to be due to impaired fatty acid metabolism, and in thinning of hair and hair loss due to insufficient keratin synthesis; also fungal skin and nail infections. Supplementation with biotin is thought to improve the condition of hair, skin and nails is cases of biotin deficiency, and improve brittle nails, and hardness and thickness of nails 31, 32, 33.

Ascorbic acid (Vitamin C):

Vitamin C is a water soluble vitamin that is obtained only from the diet mainly from citrus fruits, tomatoes, kiwifruit, some green vegetables like broccoli and Brussel sprouts and potatoes. Vitamin C is powerful antioxidant and is found in high concentrations in the skin compared to other tissues and contributes to free radicle scavenging and antioxidant photoprotection against photodamage, by reducing oxidative stress34. During the photoaging process and the natural aging process, levels of vitamin C in the skin become depleted, accompanied by a reduction in the antioxidant enzyme system34, 35, 36. Vitamin C is also essential for the biosynthesis of collagen and promotes collagen gene expression that initiates collagen biosynthesis19, 34, 37. Other properties associated with vitamin C include supporting wound healing, by stimulating skin cells to grow and migrate; also by helping skin cells repair the effects of sun damage on their DNA. Vitamin C also helps improve skin hydration, and reduces melanin production in the skin reducing the formation of age spots19. Outcomes of a clinical study indicated that vitamin C supplementation improved skin radiance, evaluated by clinical scoring using the colouring, luminosity, brightness, and transparency scale and the imperfections scale, as well as improving firmness and elasticity38.

Vitamin D3:

Vitamin D, also known as cholecalciferol or D3, is a fat soluble vitamin that is found in eggs, lean meat, oily fish, and dairy products and is also synthesised from cholesterol in the skin, in the presence of ultraviolet rays from the sun. Vitamin D is converted to its active form first in the liver to 25 dihydroxy vitamin D, then in the kidney to 1, 25 dihydroxy vitamin D. However, vitamin D supplementation is often needed to avoid deficiency, since insufficient amounts are often found in the diet and sun avoidance is promoted due to high risk of melanoma and other skin cancers. Vitamin D is important for bone and calcium metabolism and regulates use of calcium for bone formation, as well as bone resorption to release calcium into the blood when needed. Vitamin D also stimulates calcium and phosphate absorption from the intestines and promotes. Calcium is also needed for strong nails and hair. Vitamin D acts as a steroid hormone by binding to intracellular receptors and inducing expression of certain genes that produce specific vitamin D related proteins39. Vitamin D plays an important role in hair growth and development and accumulates in the hair follicle. Vitamin D receptors are also found in hair follicle. A deficiency of vitamin D is thought to contribute to hair loss40, 41, 42.

Vitamin E:

Vitamin E is a fat soluble vitamin and is a powerful antioxidant with photoprotective properties. It exists in several forms, alpha-tocopherol being the most biologically active form and is the most common form found in human skin. The amount of vitamin E in skin is reduced with aging and by exposure to UV radiation and other air pollutants43, 44, 45. D-alpha-tocopheryl succinate demonstrates antioxidant and anti-cancer properties in various animal and in vitro systems46, 47. When ingested, vitamin E accumulates in the sebaceous glands of the skin and is secreted onto the surface of the skin in the sebum, reaching the stratum corneum, where it is stored in the lipid layer. Studies have indicated that topical application of Vitamin E and oral supplementation with Vitamin E provides photoprotection from UV damage, as well as reducing the effects of photoaging such as wrinkling. Vitamin E also acts synergistically with other natural antioxidants like vitamin C to reduce oxidative damage to the skin43, 44.

Colloidal Silica:

Silica is an important trace element and is one of the most abundant in the human body and is found in the highest concentrations in connective tissues. It is important for maintaining healthy skin by improving skin strength and elasticity; also for maintaining healthy hair, nails and strong bones. Silica plays an important role in synthesis of collagen and glycosaminoglycans, both of which are important structural proteins in skin. Silica is also essential for bone mineralisation, and reduced levels are associated with aging skin and loss of bone mass leading to increased risk of osteoporosis48, 49, 50. Silica is found is foods like bananas, green beans, spinach, whole grains, and oats; also beer. However, dietary intake is often not sufficient, as absorption depends on the form of silicon ingested. Colloidal silica consists of small particles of natural mineral silica that are dispersed in water to form a natural gel, making the silica diffusible and more readily absorbed in the body, increasing its bioavailability51. In vitro studies demonstrated that orthosilicic acid, which results from acid conversion of ingested silica in the stomach to a more soluble form of silica, stimulated collagen synthesis in human skin dermal fibroblast. This was due to increasing the activity of hydroxylation enzymes required for completing the structural modifications of active collagen fibrils rather than increasing gene expression52. Orthosilicic acid supplementation in healthy volunteers with clinical signs of photoaging, was found to improve skin surface in terms of reduced wrinkles and improved elasticity48. A clinical study with healthy volunteers and signs of age damaged skin, indicated that supplementation with colloidal silica may contribute to improvement in the thickness and turgor of the skin, reduced wrinkles and improved condition of the hair and nails53.

Zinc citrate:

Zinc is an essential trace element needed by the body in small amount and it plays a vital role in many aspects of metabolism. It is a cofactor in more than 10% of all proteins including enzymes and hormones, such as the antioxidant enzyme superoxide dismutase and metalloproteinases that involved in tissue remodelling and wound healing. Skin contains about 5% of zinc found in the body, where it concentrates in the upper layers (epidermis) and is essential for normal functioning of healthy skin due to its involvement in many aspects of skin physiology. Zinc also protects skin against sun damage caused by ultraviolet irradiation due to its antioxidant properties, and is particularly important in wound healing54, 55, 56.

Selenium:

Selenium is an essential trace element needed by the body in small amount and is a potent antioxidant that protects cells against damage due to free radicles57, 58. It is an essential micronutrient for the synthesis of selenocysteine containing selenoproteins. These selenoproteins include the enzymes glutathione peroxidase and thioredoxin reductase that are key antioxidant enzymes protecting cells from oxidative stress59, 60. Selenium concentrates in high amounts in some tissues such as the lens of the eye, which are exposed to high levels of ultraviolet irradiation from the sun, and some studies suggest that selenium supplementation may reduce risk of cataract formation57. Decreased glutathione peroxidase activity has also been associated with various cancers. A study using squamous cell carcinoma cells (skin cancer) demonstrated an association with inactivation of glutathione peroxidase activity61.

What are the Contraindications/Interactions of Go Hair Skin Nails Beauty Support?

You should always check the ingredients for known allergies and to ensure you do not have any allergies or sensitivities to these ingredients. Stop using if you develop any irritation or allergy while taking Go Hair Skin Nails. Always read the label and use as directed or seek advice from your healthcare professional.

Cautions:

You should consult your healthcare professional if you are taking any prescription medication before taking Go Hair Skin Nails, as some medications may interfere with absorption of B vitamins.

Do not use:

  • Do not take this product during pregnancy or breastfeeding
  • Do not take if allergic to seafood or other seafood products, as the collagen extract in Go Hair Skin Nails is derived from marine origins
  • If you are taking prescriptive medication, please seek advice from your medical professional first before using.

What is the Dosage Recommendation for Go Hair Skin Nails Beauty Support?

Adults Dose:

Take 1 VegeCapsule once daily. Best taken with a full glass of water. Go Hair Skin Nails can be taken at any time.
Always read the label and take only as directed.

Product Size

50 VegeCapsules

References

The following references provide scientific support for the use of this product:
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  4. Thompson JM, Mirza MA, Park MK, Qureshi AA, Cho E. The role of micronutrients in alopecia areata: A Review. Am J Clin Dermatol.2017 Oct;18(5):663-679.
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