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Good Health Imaglow™  Advanced Collagen Formula | 60 Tablets

Good Health Imaglow™ Advanced Collagen Formula | 60 Tablets

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Good Health Imaglow™ Advanced Collagen Formula

What is Imaglow™?

Imaglow™ is a dietary supplement with an advanced collagen formula that provides nutrition, antioxidant protection and hydration for the skin. Imaglow’s comprehensive, skin-focused formula nourishes and rejuvenates the skin from within. Imaglow™ helps supports healthy skin by improving the appearance of skin and reducing the visible signs of aging. Imaglow™ also supports healthy nails and hair.

Why use Imaglow™?

As we age our skin changes in structure and appearance, a process that is exacerbated by environmental factors like too much exposure to the sun. Imaglow™  is a dietary supplement with an advanced collagen formula that hydrates and nourishes the skin from within, also providing antioxidant protection to help reduce skin damage. Imaglow™  helps rejuvenate the skin by managing the natural aging process as well as the effects of sun damage, by providing essential nutrients and improving moisture balance to maintain skin structure, elasticity, firmness and resilience. Imaglow™ helps improve the visible signs of aging by reducing the appearance of pigmentation (age/sun spots), fine lines and wrinkles and skin dryness. Imaglow™ also supports healthy nails and hair.

What are the Key Benefits of Imaglow™?

Imaglow™ provides an antioxidant protection for the skin as well as promoting hydration and rejuvenating ageing skin and pigmentation. It is directly beneficial for collagen (protein) structures of the skin. The combination of ingredients helps maintain skin elasticity, firmness and resilience. Imaglow™ is an affordable, high quality skin product with high amounts of collagen, compared to other competitor products.

  • Advanced collagen formula to nourish, hydrate and rejuvenate the skin from within
  • Contains nutrients that help preserve the structure of skin
  • Promotes healthy aging
  • Promotes firm, flexible and supple skin
  • Contains antioxidants to protect the skin from damage
  • Supports healthy skin nails and hair
  • Does not contain sugar or artificial sweeteners
  • Does not contain added colours, flavours, preservatives, gluten, egg, wheat or dairy

Indications:

  • Wrinkles and fine lines
  • Dry, mature and ageing skin losing its firmness and elasticity
  • Broken capillaries
  • Damaged skin from harsh sun, chemicals and heat exposure
  • Lack of collagen which results in loss of elasticity
  • Acne prone skin
  • Psoriasis, eczema and flaky skin
  • Pigmentation
  • General skin imbalances
  • Brittle and flaky nails
  • Hair that lacks shine and lustre
  • Dry and brittle hair

What is photoaging?

Continued exposure to ultraviolet (UV) radiation from the sun causes photoaging of the skin, which is premature aging, not related to actual age in chronological terms. Photoaging affects all the layers of the skin and causes major structural changes. The epidermis contains melanocytes that produce the pigment melanin. UV causes increased melanin production, which changes the colour of the skin (sun tan), but also produces sun spots or age spots that are irregular in shape and accumulate in patches. UV exposure causes oxidative stress in the skin producing free radicles that damage skin cells and their DNA. UV exposure also triggers inflammatory responses intended to help repair the damage caused. However, the inflammatory cytokines produced create further problems by inducing the production of enzymes known as matrix metalloproteinases (MMPs) by keratinocytes (skin cells) in the epidermis (outer skin layer), also by the dermal fibroblast. These MMPs degrade collagen and elastin (important structural proteins), which disrupts the structure of the skin, causing deep wrinkles and loss of skin elasticity; also, water loss, as the ability to retain moisture is compromised by the damaged skin. Extreme exposure of the skin to UV can damage the DNA and lead to skin cancer1, 2.

What is an antioxidant?

Free radicals are unstable and highly reactive chemicals produced by oxidation, which is a chemical reaction that occurs in the body as a result of normal metabolism or due to environmental factors such as UV radiation or pollution and cigarette smoke. Free radicals can cause cell damage and cell death and are thought to contribute to skin damage. Antioxidants are stable compounds that neutralise free radicals and therefore, protect against the damage they can cause. Some antioxidants like glutathione occur naturally in the body, they can also be obtained from the diet in a range of fruits and vegetables, such as Vitamin E, the most common fat-soluble antioxidant and Vitamin C, the most common water-soluble antioxidant.

What are the Ingredients of Imaglow™?

Each capsule of Imaglow contains:
  • New Zealand Marine Collagen 250mg
  • Vitamin C (Ascorbic acid) 100mg
  • Colloidal Silica 30mg
  • Hyaluronic Acid 27.5mg (Wquivalent Sodium Hyaluronic 25mg)
  • Zinc Gluconate 58.1mg  (Equiv. Zinc 7.5mg) 
  • Biotin 650mcg
  • d-α-Tocopheryl Acid Succinate 20.66mg (Equivalent Vitamin E 25IU)
  • Resveratrol (Trans) 50mg (Equivalent Polygonum cuspidatum Root 7600mg)
Imaglow™ is formulated without:

Gluten, egg, dairy, yeast, wheat, artificial sweeteners or artificial colours.

Key Ingredients:

Multicomponent supplements:

Beneficial effects on skin structure and physiology have been demonstrated using supplements containing selected clinically tested components, particularly when used in combination. These include collagen peptides, vitamins, minerals and antioxidants. Although collagen peptides alone can protect skin against the effects of damage and aging, these effects are enhanced by using multicomponent supplements3, 4.

New Zealand Marine Collagen

Collagen is one of the most abundant proteins in the body and is group of important structural proteins found in the connective tissue throughout the body that provides structural support for all tissues, as well as regulating the way different cells and tissues function. Collagen is a fibrous protein with great tensile strength and is made up of many tiny fibrils formed in a triple helix structure. There are five types of collagen distributed throughout various tissues. Type l is the most common collagen type and is found in the dermis of skin, providing support and elasticity, due to its helical structure; also in bone, tendons, ligaments, teeth and nails. The structure and amino acid composition of collagen is preserved across species which means it is biocompatible between species. This includes marine collagen, which offers an alternative collagen source for use in pharmaceuticals, cosmetics or biomedical applications and has the added benefit of making use of waste products of processing, and with no known cross species infective agents. Marine collagen is extracted from many fish species (skin and scales), and marine invertebrates like sponges, sea urchins and jellyfish, and comprises mainly type I collagen5, 6, 7, 8. Hydrolysis is an enzymatic process for reducing a protein to its constituent peptides of small chains of amino acids that are the building blocks of proteins. Hydrolysed fish collagen is a pure form of small, low molecular weight peptides, which are easily digested and more easily absorbed and distributed, with improved bioavailability over mammalian collagen and with comparable bioactive properties7, 9, 10. In vitro studies investigating the role of collagen peptides from fish skin on normal human cultured dermal fibroblast demonstrated increased elastin production, decreased matrix metalloproteinases (MMP) production and reduced elastin degradation. These effects were enhanced by the presence of antioxidants like resveratrol, indicating that supplements containing collagen peptides and antioxidants contribute to a stable extracellular matrix (ECM) produced by dermal fibroblasts4. Animal models have been used to demonstrate that marine collagen peptides promote wound healing and collagen synthesis, also enhanced skin immunity, reduced water loss, restored skin collagen and elastin levels, and reduced collagen breakdown by matrix MMPs. These findings indicate that marine collagen peptides are effective in improving skin elasticity and hydration and protecting against photoaging11, 12, 13. The outcomes of clinical studies with healthy volunteers have shown that supplementation with hydrolysed marine collagen peptides, alone or in combination with plant derived antioxidants, improved skin properties by improving the density and integrity of the collagen network, increasing collagen and elastin content, resulting in improved elasticity, skin thickness and moisture content. These studies suggest that supplementation with collagen peptides is beneficial in improving the visible signs of aging11, 14, 15, 16, 17.

Ascorbic acid (Vitamin C):

Vitamin C is a powerful antioxidant that is obtained from the diet and it is found in high concentrations in the skin compared to other tissues. Vitamin C is essential for the biosynthesis of collagen and promotes collagen gene expression that initiates collagen biosynthesis14, 18, 19. Vitamin C contributes to free radicle scavenging and antioxidant photoprotection against photodamage, by reducing oxidative stress19. During the photoaging process and the natural aging process, levels of vitamin C in the skin become depleted, accompanied by a reduction in the antioxidant enzyme system19, 20. Other properties associated with vitamin C include supporting wound healing, by stimulating skin cells to grow and migrate; also by helping skin cells repair the effects of sun damage on their DNA. Vitamin C also helps improve skin hydration and reduces melanin production in the skin, reducing the formation of age spots14, 19. Outcomes of a clinical study indicated that vitamin C supplementation improved skin radiance, evaluated by clinical scoring using the colouring, luminosity, brightness, and transparency scale and the imperfections scale, as well as improving firmness and elasticity21.

Colloidal Silica:

Silica is an important trace element and is one of the most abundant in the human body. It is important for maintaining healthy skin by improving skin strength and elasticity; also for maintaining healthy hair, nails and strong bones. Silica is found in the highest concentrations in connective tissues, particularly in the aorta, trachea, bone, and skin. Silica plays an important role in synthesis of collagen and glycosaminoglycans, both of which are important structural proteins in skin. Silica is also essential for bone mineralisation, and reduced levels are associated with aging skin and loss of bone mass leading to increased risk of osteoporosis22, 23, 24. Silica is found is foods like bananas, green beans, spinach, whole grains, and oats; also beer. However, dietary intake is often not sufficient, as absorption depends on the form of silicon ingested. Colloidal silica consists of small particles of natural mineral silica that are dispersed in water to form a natural gel, making the silica diffusible and more readily absorbed in the body, increasing its bioavailability25. In vitro studies demonstrated that orthosilicic acid, which results from acid conversion of ingested silica in the stomach to a more soluble form of silica, stimulated collagen synthesis in human skin dermal fibroblast. This was due to increasing the activity of hydroxylation enzymes required for completing the structural modifications of active collagen fibrils rather than increasing gene expression26. Orthosilicic acid supplementation in healthy volunteers with clinical signs of photoaging, was found to improve skin surface in terms of reduced wrinkles and improved elasticity22. A clinical study with healthy volunteers and signs of age damaged skin, indicated that supplementation with colloidal silica may contribute to improvement in the thickness and turgor of the skin, reduced wrinkles and improved condition of the hair and nails27.

Hyaluronic Acid:

Hyaluronic acid is a key component of the extracellular matrix (ECM) and is major functional protein in the skin. Hyaluronic acid is a proteoglycan which comprises a core protein attached to a glycosaminoglycan (long chain sugar) and has the ability bind and retain water molecules. Changes in hyaluronic acid structure and distribution in skin is a key feature of aging, along with changes in the hyaluronidase enzymes that degrade hyaluronic acid, particularly in relation to photoaged skin28, 29, 30. Animal and in vitro studies demonstrated that ingested hyaluronic acid reaches the skin and stimulates dermal fibroblast proliferation and synthesis of hyaluronic acid. The outcome of clinical studies indicated that ingestion of hyaluronic acid increased water content and improved smoothness of dry skin30. The effect of ingested hyaluronic acid on wrinkles was measured by image analysis and questionnaire in healthy volunteers and found to reduce wrinkles and improve skin lustre and suppleness31.

Zinc Gluconate:

Zinc is an essential trace element needed by the body in small amounts and it plays a vital role in many aspects of metabolism. It is a cofactor in more than 10% of all proteins including enzymes and hormones, such as the antioxidant enzyme superoxide dismutase and metalloproteinases that are involved in tissue remodelling and wound healing. Skin contains about 5% of all zinc found in the body, where it concentrates in the upper layers (epidermis) and is essential for normal functioning of healthy skin due to its involvement in many aspects of skin physiology32. Zinc also protects skin against sun damage caused by UV irradiation due to its antioxidant properties, and is particularly important in wound healing32, 33, 34.

Biotin:

The B vitamins are a family of water soluble vitamins that play important roles in many essential physiological processes35. Biotin or vitamin B7 is an essential cofactor for the carboxylase enzyme that is involved in many metabolic pathways particularly fatty acid synthesis, and amino acid metabolism. Biotin is an essential factor for synthesis of keratin, an integral structural protein of hair, skin and nails. Biotin deficiency results in dermatitis which is thought to be due to impaired fatty acid metabolism, and in hair loss due to insufficient keratin synthesis. Supplementation with biotin is thought to improve condition of hair, skin and nails in cases of biotin deficiency36, 37, 38.

d-α-Tocopheryl Acid Succinate:

Vitamin E is a fat soluble vitamin and is a powerful antioxidant with photoprotective properties that exists in several forms, alpha-tocopherol being the most common form found in human skin. The amount of vitamin E in the skin is reduced with aging and by exposure to UV radiation and other air pollutants39, 40. Imaglow contains vitamin E as d-alpha-tocopheryl succinate, which is a natural form of vitamin E often used in dietary supplements as it is more stable and has greater bioavailability compared to other forms of vitamin E41. D-alpha-tocopheryl succinate demonstrates antioxidant and anti-cancer properties in various animal and in vitro systems42, 43. When ingested, vitamin E accumulates in the sebaceous glands of the skin and is secreted onto the surface of the skin in the sebum, reaching the stratum corneum, where it is stored in the lipid layer. Studies have indicated that topical application of Vitamin E and oral supplementation with Vitamin E provides photoprotection from UV damage, as well as reducing the effects of photoaging such as wrinkling. Vitamin E also acts synergistically with other natural antioxidants like vitamin C to reduce oxidative damage to the skin39, 40.

Resveratrol (Trans):

Resveratrol is a natural polyphenol antioxidant belonging to the stilbene group of phytochemicals, that is present in red wines, grapes (seeds and skin), and the roots of Polygonum cuspidatum, also known as Japanese Knotweed, an herbaceous perennial plant belonging to the Polygonaceae family native to Asia and North America. Polygonum has been used in traditional Chinese and Indian (Ayurvedic) medicine for centuries to treat several ailments including circulatory problems, liver diseases like jaundice and hepatitis, and cough. Several pharmacologically active compounds have been isolated from extracts of Polygonum including stilbenes like resveratrol, flavonoids like quercetin and catechin, amongst others, which have antivirus, antimicrobial, anti-inflammatory, neuroprotective, and cardioprotective activities.44,45 Resveratrol also has potent anti-inflammatory and antioxidant activity, as demonstrated in a clinical study with healthy subjects in which free radicle generation and inflammatory markers were reduced following ingestion with Polygonum extract46. Animal and in vitro studies have demonstrated that resveratrol provides protection against UV irradiation that can lead to skin cancers by several mechanisms, including protection against free radical formation, regulating apoptosis (programmed cell death), inhibiting the production of inflammatory mediators in skin cells, and modulating several mediators of cell proliferation47. In vitro studies with human skin cells have indicated that resveratrol has anti-aging properties that may help reduce the visible signs of aging, by reducing free radicle generation, reducing production of matrix metalloproteinase enzymes that destroy collagen and elastin, increasing production of collagen following UV irradiation, and inhibiting production of inflammatory mediators48. Animal models of wound healing have demonstrated that resveratrol helps wound healing by increasing antioxidant activity and by increasing collagen production in the wound49.

What are the Contraindications/Interactions of Imaglow™?

There are no documented interactions within the recommended dosage. However, you should always check the ingredients for known allergies and to ensure you do not have any allergies or sensitivities to these ingredients. Stop using if you develop any irritation or allergy while taking Imaglow. Always read the label and use as directed or seek advice from your healthcare professional.

Caution:

Imaglow™  should not be used if:
  • you have an allergy to seafood or other seafood products, as the collagen extract in Imaglow is derived from marine origins.
  • you are pregnant or breastfeeding, without discussion with your doctor

What is the Dosage Recommendation for Imaglow™?

Adults Dosage:

Take two capsules daily with food for up to three months to achieve maximum effect. For maintenance this can be reduced to one capsule daily after three months.

Product Size

60 Tablets

References

The following references provide scientific support for the use of this product:
  1. Fagot D, Asselineau D, Bernerd F. Direct role of human dermal fibroblasts and indirect participation of epidermal keratinocytes in MMP-1 production after UV-B irradiation. Arch Dermatol Res 2002; 293: 576–583.
  2. Quan T, Qin Z, Xia W, Shao Y, Voorhees JJ, Fisher GJ. Matrix-degrading Metalloproteinases in Photoaging. J Investig Dermatol Symp Proc. 2009 Aug; 14(1): 20–24.
  3. Birnbaum J, Le Moigne A, Dispensa L, Buchner L. A Review of Clinical Trials Conducted With Oral, Multicomponent Dietary Supplements for Improving Photoaged Skin. J Drugs Dermatol.2015 Dec;14(12):1453-61.
  4. Edgar S, Hopley B, Genovese L, Sibilla S, Laight D, Shute J. Effects of collagen-derived bioactive peptides and natural antioxidant compounds on proliferation and matrix protein synthesis by cultured normal human dermal fibroblasts. Sci Rep.2018 Jul 11;8(1):10474.
  5. Silva TH, -Silva JM, ALP, Domingues A, Bayon Y, L. Reis R. Marine Origin Collagens and Its Potential Applications. Mar. Drugs 2014, 12, 5881-5901;
  6. Rahman MA. Collagen of Extracellular Matrix from Marine Invertebrates and Its Medical Applications. Mar. Drugs 2019, 17, 118;
  7. Carvalho AM, Marques AP, Silva TH, Reis RL. Evaluation of the Potential of Collagen from Codfish Skin as a Biomaterial for Biomedical Applications. Mar Drugs.2018 Dec 8;16(12). pii: E495.
  8. Subhan F, Ikram M, Shehzad A, Ghafoor A. Marine Collagen: An Emerging Player in Biomedical applications. J Food Sci Technol (August 2015) 52(8):4703–4707
  9. Sripriya R, Kumar R. A Novel Enzymatic Method for Preparation and Characterization of Collagen Film from Swim Bladder of Fish Rohu (Labeo rohita). Food and Nutrition Sciences, 2015, 6, 1468-1478
  10. Sibilla S, Godfrey M, Brewer S, Budh-Raja A, and Genovese L. An Overview of the Beneficial Effects of Hydrolysed Collagen as a Nutraceutical on Skin Properties: Scientific Background and Clinical Studies. The Open Nutraceuticals Journal, 2015, 8, 29-42
  11. De Luca C, Mikhal’chik EV, Suprun MV, Papacharalambous M, Truhanov AI, Korkina LG. Skin Antiageing and Systemic Redox Effects of Supplementation with Marine Collagen Peptides and Plant-Derived Antioxidants: A Single-Blind Case-Control Clinical Study. Oxid Med Cell Longev2016; 2016: 4389410.
  12. Tanaka M., Koyama Y.-I., Nomura Y. Effects of collagen peptide ingestion on UV-B-induced skin damage. Bioscience, Biotechnology and Biochemistry. 2009;73(4):930–932
  13. Fan J., Zhuang Y., Li B. Effects of collagen and collagen hydrolysate from jellyfish umbrella on histological and immunity changes of mice photoaging. Nutrients. 2013;5(1):223–233.
  14. Costa A, Pegas Pereira ES, Assumpção EC, Calixto Dos Santos FB, Ota FS, de Oliveira Pereira M, Fidelis MC, Fávaro R, Barros Langen SS, Favaro de Arruda LH, Abildgaard EN. Assessment of clinical effects and safety of an oral supplement based on marine protein, vitamin C, grape seed extract, zinc, and tomato extract in the improvement of visible signs of skin aging in men. Clin Cosmet Investig Dermatol. 2015 Jun 29;8:319-28.
  15. Kim D-U, Chung H-C, Choi J, Sakai Y, Lee B-Y. Oral Intake of Low-Molecular-Weight Collagen Peptide Improves Hydration, Elasticity, and Wrinkling in Human Skin: A Randomized, Double-Blind, Placebo-Controlled Study
  16. Asserin J, Lati E, Shioya T, Prawitt J. The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. J Cosmet Dermatol.v2015;4:291–330.
  17. Borumand M, Sibilla S. Daily consumption of the collagen supplement Pure Gold Collagen reduces visible signs of aging. Clin Interv Aging. 2014;9:1747–1758.
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  19. Pullar JM, Carr AC, Vissers MCM. The Roles of Vitamin C in Skin Health. Nutrients 2017, 9, 866.
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  21. Dumoulin M, Gaudout D, Lemaire B. Clinical effects of an oral supplement rich in antioxidants on skin radiance in women. Clin Cosmet Investig Dermatol.2016 Oct 18;9:315-324.
  22. Araújo LA, Addor F, Campos PM. Use of silicon for skin and hair care: an approach of chemical forms available and efficacy. An Bras Dermatol2016 May-Jun; 91(3): 331–335.
  23. Jurkić LM, Cepanec I, Pavelić SK, Pavelić K. Biological and therapeutic effects of ortho-silicic acid and some ortho-silicic acid-releasing compounds: New perspectives for therapy. Nutr Metab (Lond)2013; 10: 2.
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  25. Sripanyakorn S, Jugdaohsingh R, Dissayabutr W, Anderson SHC, Thompson RPH, Powell JJ. The comparative absorption of silicon from different foods and food supplements. Br J Nutr. 2009 September ; 102(6): 825–834.
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  27. Lassus A. Colloidal silicic acid for oral and topical treatment of aged skin, fragile hair and brittle nails in females Journal of international medical research, 1993; 21; 209-215.
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  31. Oe M, Sakai S, Yoshida H, Okado N, Kaneda H, Masuda Y, Urushibata O. Oral hyaluronan relieves wrinkles: a double blinded, placebo-controlled study over a 12-week period. Clin Cosmet Investig Dermatol.2017 Jul 18;10:267-273
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  33. Ogawa Y, Kinoshita M, Shimada S, Kawamura T. Zinc and Skin Disorders. Nutrients 2018, 10, 199;
  34. Rostan, E.F.; DeBuys, H.V.; Madey, D.L.; Pinnell, S.R. Evidence supporting zinc as an important antioxidant for skin. Int. J. Dermatol. 2002, 41, 606–611.
  35. Kennedy DO. B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review. Nutrients 2016, 8, 68.
  36. Seymons K, De Moor A, De Raeve H, Lambert J. Dermatologic signs of biotin deficiency leading to the diagnosis of multiple carboxylase deficiency. Pediatr Dermatol.2004 May-Jun;21(3):231-5.
  37. Lipner SR, Scher RK Biotin for the treatment of nail disease: what is the evidence? J Dermatolog Treat.2018 Jun;29(4):411-414.
  38. Patel PP, Swink SM, Castelo-Soccio L. A Review of the Use of Biotin for Hair Loss. Skin Appendage Disord 2017;3:166–169
  39. Thiele JJ, Hsieh SN, Ekanayake-Mudiyanselage S. Vitamin E: Critical review of its current use in cosmetic and clinical dermatology. Dermatol Surg. 2005;31:805–13.
  40. Thiele JJ, Hsieh SN, Ekanayake-Mudiyanselage S. Vitamin E in human skin: Organ-specific physiology and considerations for its use in dermatology. Molecular Aspects of Medicine 28 (2007) 646–667
  41. Jensen SK. Lauridsen C. Alpha-tocopherol stereoisomers. Vitam Horm.2007;76:281-308.
  42. Neuzil J. Vitamin E succinate and cancer treatment: a vitamin E prototype for selective antitumour activity. Br J Cancer.2003 Nov 17;89(10):1822-6.
  43. Ranard KM, Erdman JW. Nutr Rev.2018 Mar 1;76(3):141-153. Effects of dietary RRR α-tocopherol vs all-racemic α-tocopherol on health outcomes.
  44. Zhang H, Li C, Kwok S-T, Zhang Q-W, Chan S-W. A Review of the Pharmacological Effects of the Dried Root of Polygonum cuspidatum (Hu Zhang) and Its Constituents. Evidence-Based Complementary and Alternative Medicine Volume 2013, Article ID 208349, 13 pages.
  45. Galiniak S, Aebisher D, and Bartusik-Aebisher D. Health benefits of resveratrol administration. Acta Biochim Pol. 2019 Feb 28;66(1):13-21
  46. Ghanim H, Sia CL, Abuaysheh S, Korzeniewski K, Patnaik P. An antiinflammatory and reactive oxygen species suppressive effects of an extract of Polygonum cuspidatum containing resveratrol. J Clin Endocrinol Metab.2010 Sep;95(9):E1-8.
  47. Aziz SW, Aziz MH. Protective molecular mechanisms of resveratrol in UVR-induced Skin carcinogenesis. Photodermatol Photoimmunol Photomed.2018 Jan;34(1):35-41.
  48. Subedi L, Lee TH, Wahedi HM, Baek SH, Kim SY. Resveratrol-Enriched Rice Attenuates UVB-ROS-Induced Skin Aging via Downregulation of Inflammatory Cascades. Oxid Med Cell Longev.2017;2017:8379539
  49. Yaman I, Derici H, Kara C Kamer E, Diniz G, et al. Effects of resveratrol on incisional wound healing in rats. Surgery Today. 2013;43(12):1433–1438