Artemis Nerve & Skin Rescue Oil | 50ml

Artemis Nerve & Skin Rescue Oil 

What is Nerve & Skin Rescue Oil?

Nerve and Skin Rescue Oil is a an extract of St John’s Wort, one of the most researched medicinal plants, prepared in extra virgin olive oil, resulting in a concentrated oil containing compounds with known effectiveness for skin problems. The oil extract also has properties that help in managing pain and in wound healing.

Why use Nerve & Skin Rescue Oil?

Our skin takes the brunt of environmental assaults such as harsh UV rays from the sun, toxic pollutants and cold drying winds. It is important to protect and support our skin so that it can continue to do its important job of protecting us, particularly as we age. Nerve and Skin Rescue Oil provides a natural herbal remedy that soothes and nourishes the skin. Nerve and Skin Rescue Oil is an extract of St John’s Wort, one of the most researched medicinal plants, in extra virgin olive oil. The resulting concentrated oil is rich in compounds with known effectiveness for skin problems and with properties that can ease nerve pain and muscular discomfort, help reduce skin damage, and promote wound healing.

What are the Key Benefits of Nerve & Skin Rescue Oil?

• Traditional medicinal plant formula 
• Contains essential oil of St John’s Wort, a well-researched herbal medicine
• Helps manage pain, soothe muscular discomfort and promote wound healing
• Soothes skin conditions that cause discomfort
• Protects the skin from the harsh effects of our environment
• All ingredients are GE free 
• Does not contain artificial colours or fragrances, mineral oils, parabens, sulphates or synthetic fillers

How does pain work?

Pain is a signal sent out by the brain, transmitted by nerves and picked up by various pain sensors throughout the body. Although unpleasant, pain is natural warning sign to our body of injury, illness or potential danger. There are different types of pain; acute pain is an immediate local response, such as to a burn or an injury and stops as soon as the cause of the pain is resolved. However, if the pain persists after the damage has healed, it becomes chronic pain and can be due to a progressive disorder like arthritis or nerve damage. Specific pain receptors called nociceptors, pick up the local pain signals and are stimulated by heat, pressure, mechanical forces like a cut, and chemicals like inflammatory mediators. However nerve pain works differently and has a different sensation, more like burning or electric shocks compared to throbbing or aching of nociceptive pain and is usually due to a damaged or irritated nerve.

Why protect your skin?

The skin is our largest organ and plays an important role as a protective barrier against infection, injury, and harmful effect of the sun’s rays. Our skin also helps prevent dehydration due to loss of moisture, regulates our body temperature and produces vitamin D essential for healthy bones. This hard working organ has two layers. The outer epidermis is made up of keratinocytes that are constantly renewed as cells at the top die off; it produces keratin, an important structural protein and melanin, the pigment that protects us from UV radiation that causes skin damage. The dermis contains small blood vessels, nerves, sweat glands and hair follicles with their sebaceous glands that produce the oily sebum to lubricate the skin. The dermis also contains collagen and elastin, which give skin its elasticity and flexibility. Most skin disorders are a result of a breakdown in the barrier function of the skin and loss of moisture. They include inflammatory allergic skin conditions skin conditions like dermatitis and eczema, which cause redness and itching; also psoriasis, a non-allergic autoimmune condition that causes dry scaly patches. Our environment can cause considerable damage to our skin, such as the harsh UV rays of the sun resulting in structural damage even cancer; extreme weather that can dry the skin and air pollutants that can cause damaging free radical formation.

What is transepidermal water loss?

Transepidermal water loss is when water passes up through the skin and is lost by evaporation through the epidermis. It is an indication of damaged epidermal barrier function of the skin and can lead to dehydration of the skin and problems like dry scaly skin, dermatitis and eczema.

How does a wound heal?

Tissue injury of any sort triggers a complex process known as wound healing that involves several types of cell and a cocktail of chemicals produced by those cells. The first response to injury is haemostasis, preventing loss of blood by plugging damaged blood vessels. Next is inflammation in which specialised cells remove or debride damage tissues, followed by epithelialisation, which is production of new skin cells (keratinocytes) to seal the wound. A scar is the visible sign of wound healing once the exposed tissue has been covered up.   

What are the Ingredients of Nerve and Skin Rescue Oil?

Nerve and Skin Rescue Oil is made from fresh flower heads of wild alpine St John's Wort, macerated in certified organic extra virgin olive oil and cold pressed.

Key Ingredient:

St John's Wort (Hypericum perforatum):

St John’s Wort is a perennial flowering plant with yellow flowers, native to parts of Europe, Asia and North Africa, but commonly found in meadows and woods worldwide. It has been used for centuries to treat nervous conditions as wells as for its antibacterial, antiviral and anti-inflammatory properties. It is also a traditional topical remedy for treating superficial wounds, scars, burns and dermatitis and is used in contemporary herbal medicine as a topical treatment for various skin disorders and as an ingredient in skin care products, including massage oils. St John’s Wort is a well-researched medicinal plant and in contemporary herbal medicine alcohol extracts of the dried flowers and leaves are widely used to prepare a liquid or tea for use as an herbal remedy for mild to moderate depression¹. St John’s Wort also has small oil glands in the leaves from which an oil extract can be obtained. Preparations of St John’s Wort topical application of oils or tinctures are regularly used in herbal medicine for treating several skin and muscle problems including minor wounds and burns, sunburn, bruises, ulcers and myalgia (muscle pain)². Extracts of St John’s Wort contain several bioactive components, of which hypericin and hyperforin are thought to be the major pharmacologically active compounds that contribute to the biological properties of St John's Wort, including its antidepressive and analgesic effects^3.

Analgesic application

Several preclinical animal studies have demonstrated the potential of St John’s Wort extract for use in pain relief due to its antinociceptive (blocking the detection of painful stimuli by sensory neurons) and analgesic properties (relieves the symptoms of pain), which supports its traditional use for treating painful conditions. These studies included conditions with increased sensitivity to pain stimuli (hyperalgesia), and when used with opioid analgesic medications, St John’s Wort extract was found to provide increased pain relief. Clinical studies have also suggested that St John’s Wort extract may be effective for relief of dental pain^4.

Dermatological applications

Hypericin, hyperforin and also flavonoids that are found in St John’s Wort are thought to contribute to the anti-inflammatory, antimicrobial, antioxidant and skin restorative properties that make extract of St John’s Wort a useful topical treatment for skin problems, including atopic dermatitis, psoriasis and herpes infections. The most commonly used topical preparation is made using fresh or dried flowers crushed into a vegetable oil and the resulting oil extract is rich in the active ingredients hypericin, hyperforin as well as flavonoids like quercetin^2. Hyperforin in oil extract of St John’s Wort stimulates epidermal skin cell (keratinocyte) differentiation, which is thought to help to reduce transepidermal water loss. Oil extract of St John’s Wort also has powerful antioxidant properties due to its flavonoid content and this is thought to provide protection again skin damage due to irradiation from the sun^{2, 5.} A study using various oil extracts of St John’s Wort demonstrated anti-inflammatory and antimicrobial activity on irritated skin^6. A cream containing extract of St John’s Wort was shown to be an effective topical treatment in a study of patients with mild to moderate eczema^7. A topical preparation of St John’s Wort oil mixed with neem oil (Azadirachta indica) was found to be helpful for head and neck cancer patients undergoing radiotherapy in treatment of radiation dermatitis, a common problem following cancer radiotherapy^8.

Wound healing

The wound healing properties of St John's Wort oil were demonstrated in experimental animal models of skin injury and shown to include antiinflamatory and antibacterial actions, as well as the promotion of new growth of skin cells over the wound (epithelialisation) and stimulation of collagen synthesis, which enhances the tissue regeneration and wound healing process^{9, 10.} An animal study comparing the effects of silver sulfadiazine with St John’s Wort extract found it was as effective for wound healing in burn injuries when applied topically^11. These animal studies were supported by clinical evidence. In a case study the beneficial effects of an oily extract of St John's Wort was demonstrated in the treatment of pressure sore wounds in an intensive care unit^12. An ointment containing extracts of St John’s Wort was found to promote caesarean wound healing with reduced scar formation^13.

What are the Contraindications/Interactions of Nerve and Skin Rescue Oil?

There are no documented herb-drug interactions within the recommended dosage. Studies have indicated that St. John's Wort is well tolerated with few side effects. It is however, known to cause photosensitivity (sensitivity to sunlight)^2, therefore caution is advised when skin is exposed to direct sunlight. You should always check the ingredients for known allergies and to ensure you do not have any allergies or sensitivities to these ingredients. Stop using if you develop any irritation or allergy while taking Nerve and Skin Rescue Oil. Always read the label and use as directed or seek advice from your healthcare professional.

Caution:

Nerve and Skin Rescue Oil should be used with caution if you:

• are pregnant or breast-feeding
• develop a reaction or irritation to any ingredients in Nerve and Skin Rescue Oil
• are taking prescription medications, as St John’s Wort may interact with some medications, usually only when taken orally, however it is advisable to consult your doctor before use

What are the Directions for using Nerve and Skin Rescue Oil?

Dosage:

Apply a thin layer of oil to the affected area three times daily, or more frequently for acute conditions.

For best results:

If you are using Nerve and Skin Rescue Oil for a nerve related problem, then take in conjunction with Stress Relief Tea to best support the nervous system.

Special instructions:

Store in a cool place and out of direct sunlight. Over time, Nerve and Skin Rescue Oil may discolour as it is a natural product, but this does not affect the efficacy or quality of the oil.

Product Size:

50ml

References

The following references provide scientific support for the use of this product:

1. Apaydin EA, Maher AR, Shanman R, Booth MS, Miles JN, Sorbero ME, Hempel S. A systematic review of St. John's wort for major depressive disorder. Syst Rev 2016 Sep 2;5(1):148. 
2. Wölfle U, Seelinger G, Schempp CM. Topical application of St. John's wort (Hypericum perforatum). Planta Med. 2014 Feb;80(2-3):109-20. 
3. Nahrstedt A Butterweck V. Biologically active and other chemical constituents of the herb of Hypericum perforatum L. Pharmacopsychiatry 1997 Sep;30 Suppl 2:129-34 
4. Galeotti N. Hypericum perforatum (St John's wort) beyond depression: A therapeutic perspective for pain conditions. J Ethnopharmacol 2017 Mar 22;200:136-146 
5. Meinke MC, Schanzer S, Haag SF, Casetti F, Müller ML, Wölfle U, Kleemann A, Lademann J, Schempp CM. In vivo photoprotective and anti-inflammatory effect of hyperforin is associated with high antioxidant activity in vitro and ex vivo. Eur J Pharm Biopharm.2012 Jun;81(2):346-50. 
6. Arsić I, Zugić A, Tadić V, Tasić-Kostov M, Mišić D, Primorac M, Runjaić-Antić D. Estimation of dermatological application of creams with St. Johnʼs Wort oil extracts. Molecules 2011; 17: 275-294
7. Schempp CM, Windeck T, Hezel S, Simon JC. Topical treatment of atopic dermatitis with St. Johnʼs wort cream – a randomized, placebo controlled, double blind half-side comparison. Phytomedicine 2003;10 (Suppl. 04) 31-37 
8. Franco P, Rampino M, Ostellino O, Schena M, Pecorari G, et al. Management of acute skin toxicity with Hypericum perforatum and neem oil during platinum-based concurrent chemo-radiation in head and neck cancer patients. Med Oncol.2017 Feb;34(2):30. 
9. Prisăcaru AI, Andriţoiu CV, Andriescu C, Hăvârneanu EC, Popa M, Motoc AG, Sava A. Evaluation of the wound-healing effect of a novel Hypericum perforatum ointment in skin injury. Rom J Morphol Embryol 2013;54(4):1053-9.
10. Nayak SB, Isik K, Marshall JR. Wound-Healing Potential of Oil of Hypercium perforatum in Excision Wounds of Male Sprague Dawley Rats. Adv Wound Care (New Rochelle).2017 Dec 1;6(12):401-406. 
11. Kıyan S, Uyanıkgil Y, Altuncı YA, Çavuşoğlu T, Çetin Uyanıkgil EÖ, Karabey F. Investigation of acute effects of Hypericum perforatum (St. John's Wort-Kantaron) treatment in experimental thermal burns and comparison with silver sulfadiazine treatment. Ulus Travma Acil Cerrahi Derg 2015 Sep;21(5):323-36. 
12. Yücel A, Kan Y, Yesilada E, Akın O. Effect of St.John's wort (Hypericum perforatum) oily extract for the care and treatment of pressure sores; a case report. J Ethnopharmacol.2017 Jan 20;196:236-241. 
13. Samadi S, Khadivzadeh T, Emami A, Moosavi NS, Tafaghodi M, Behnam HR. The effect of Hypericum perforatum on the wound healing and scar of cesarean. J Altern Complement Med. 2010 Jan;16(1):113-7.